Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist medication used to treat type 2 diabetes and manage weight long-term. It’s available as a weekly injection or a daily tablet. Semaglutide works by increasing insulin production, reducing sugar released into the blood, and slowing digestion. This helps lower blood sugar and HbA1c levels. For type 2 diabetes, it’s used when other medications haven’t controlled blood sugar levels.